ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2015, Vol. 46 ›› Issue (6): 882-888.doi: 10.11843/j.issn.0366-6964.2015.06.002

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Heterogeneous Nuclear Ribonucleoprotein and Virus Replication

FENG Xiao-hui,TANG Cheng,ZHU Xin,YUE Hua*   

  1. (College of Life Science and Technology,Southwest University for Nationalities,Chengdu 610041,China)
  • Received:2014-09-15 Online:2015-06-23 Published:2015-06-23

Abstract:

Heterogeneous nuclear ribonucleoproteins (hnRNPs) is a family of highly conserved RNA-binding proteins,which widely exist in most kinds of tissues and cells.HnRNPs primarily participate in pre-mRNA slicing,mRNA transport,mRNA stability and post-transcriptional regulation in physiological condition.For the past few years,studies have found that hnRNPs could affect viral replication through multiple mechanisms,including binding with viral nuclei acid or viral protein,and regulating apoptosis of host cells.This paper reviews the progress in the study of the relation between heterogeneous nuclear ribonucleoprotein and virus replication.

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